Thrombotic Processes in Multiple Sclerosis as Manifestation of Innate Immune Activation
نویسندگان
چکیده
منابع مشابه
Thrombotic Processes in Multiple Sclerosis as Manifestation of Innate Immune Activation
INTRODUCTION Multiple sclerosis (MS) is a chronic demyelinating inflammatory disease of the central nervous system (CNS) affecting prevalently young adults (1, 2). The pathogenesis of MS has long been attributed to self-reactive T cells but recently the relevant role of B cells has also been recognized (2, 3). Furthermore, it has been demonstrated that innate immunity has a pivotal role in the ...
متن کاملP 60: The Effect of Melatonin as a Therapeutic Goal on Multiple Sclerosis Through Immune Processes
Multiple sclerosis is an autoimmune disease of the central nervous system which is accompanied by demyelinating the neurons. The imbalance between the T cell effectors and T cell regulators is thought to have a role in the pathogenesis of the disease. Melatonin is a hormone that is secreted by pineal gland which has an important role in circadian rhythm and immune-modulatory effects. Melatonin ...
متن کاملOptic neuritis as onset manifestation of multiple sclerosis A single center study in North of Iran
Background: Multiple sclerosis (MS) is an inflammatory and demyelinating disease of central nervous system (CNS). The aim of the present study was to determine the type and the frequency of initial presenting symptoms in patients with MS and their relation with demographic characteristics in Babol, northern Iran. Methods: All patients of this study were recruited over a ten year period fr...
متن کاملp 60: the effect of melatonin as a therapeutic goal on multiple sclerosis through immune processes
multiple sclerosis is an autoimmune disease of the central nervous system which is accompanied by demyelinating the neurons. the imbalance between the t cell effectors and t cell regulators is thought to have a role in the pathogenesis of the disease. melatonin is a hormone that is secreted by pineal gland which has an important role in circadian rhythm and immune-modulatory effects. melatonin ...
متن کاملThe function of epigenetic processes in multiple sclerosis: review article
Multiple Sclerosis (MS) is a chronic neurological and inflammatory disorder that affects the nervous system. The etiology of MS is unknown, but genetic and environmental factors are involved in its pathogenesis. There is increasing evidence suggesting the role of epigenetic mechanisms in the pathogenesis of multiple sclerosis. Lack of vitamin D, smoking, and Epstein barr virus can cause epigene...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2014
ISSN: 1664-2295
DOI: 10.3389/fneur.2014.00119